BORA

Across TCGA cell cohorts, BORA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,461 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BORA-associated GO terms across cancer lineages are Mitotic metaphase chromosome alignment, Metaphase chromosome alignment, and Attachment of mitotic spindle microtubules to kinetochore. Each is linked with BORA in more than 19 cancer types. Because this analysis shows association rather than direction, both BORA-to-partner and partner-to-BORA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic metaphase chromosome alignment grouped by BORA-low versus BORA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BORA→partner) and Y-score (partner→BORA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic metaphase chromosome alignment →	+0.152	+1.002	.001	.001	3	20
BONE	Metaphase chromosome alignment →	+0.148	+1.002	.003	.001	3	19
UPPER_AERODIGESTIVE_TRACT	Attachment of mitotic spindle microtubules to kinetochore →	+0.140	+1.414	<.001	<.001	3	19
SOFT_TISSUE	Attachment of spindle microtubules to kinetochore →	+0.151	+1.171	<.001	<.001	3	19
BONE	Positive regulation of mitotic sister chromatid separation →	+0.194	+0.992	.009	.003	3	18
KIDNEY	Regulation of chromosome separation →	+0.158	+1.060	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,461 associations by consensus.

Mitotic metaphase chromosome alignment by BORA expression — BONE

Explore this box plot interactively →