BOP1

Across TCGA cell cohorts, BOP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,235 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BOP1-associated GO terms across cancer lineages are rRNA metabolic process, Ribosome biogenesis, and Nucleosome disassembly. Each is linked with BOP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both BOP1-to-partner and partner-to-BOP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA metabolic process grouped by BOP1-low versus BOP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOP1→partner) and Y-score (partner→BOP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	rRNA metabolic process →	+0.148	+0.909	<.001	<.001	3	18
LUNG_SCLC	Ribosome biogenesis →	+0.129	+0.913	<.001	<.001	3	17
BONE	Nucleosome disassembly →	+0.174	+1.557	.001	<.001	3	17
BONE	Protein-DNA complex disassembly →	+0.157	+1.568	.003	<.001	3	17
LUNG_SCLC	Ribosomal small subunit biogenesis →	+0.128	+0.696	<.001	<.001	3	17
LUNG_SCLC	Ribosome assembly →	+0.097	+0.850	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,235 associations by consensus.

rRNA metabolic process by BOP1 expression — LUNG_SCLC

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