Across TCGA pan-cancer cohorts, BOLA3P4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of BOLA3P4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where BOLA3P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BOLA3P4 is over-expressed in tumor, although a few such as THCA and PAAD show the opposite, repressed pattern.

BRCA, THCA, and PAAD are the cancer types where BOLA3P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BOLA3P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	+0.087	.014	6	view →
THCA	Female	All	−0.163	<.001	5	view →
PAAD	All	All	−0.335	.030	4	view →
READ	All	III,IV	−0.280	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: BOLA3P4 RNA expression & survival · all BOLA3P4 data types