Across TCGA pan-cancer cohorts, BOLA3P3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BOLA3P3’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where BOLA3P3 RNA is repressed in tumor relative to normal tissue. In most cancer types BOLA3P3 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.
COAD, LIHC, and READ are the cancer types where BOLA3P3 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BOLA3P3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.