Across TCGA pan-cancer cohorts, BOLA3P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of BOLA3P2’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where BOLA3P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BOLA3P2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
LUAD, BRCA, and KICH are the cancer types where BOLA3P2 tumor–normal differential expression is most reproducible.