Across TCGA cell cohorts, BOLA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,744 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BOLA2-associated GO terms across cancer lineages are [2Fe-2S] cluster assembly, Iron-sulfur cluster assembly, and Metallo-sulfur cluster assembly. Each is linked with BOLA2 in more than 15 cancer types. Because this analysis shows association rather than direction, both BOLA2-to-partner and partner-to-BOLA2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA2→partner) and Y-score (partner→BOLA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	[2Fe-2S] cluster assembly →	+0.172	+0.879	<.001	<.001	3	16
LUNG_SCLC	Iron-sulfur cluster assembly →	+0.153	+1.068	<.001	<.001	3	12
LUNG_SCLC	Metallo-sulfur cluster assembly →	+0.153	+1.068	<.001	<.001	3	12
BONE	Pyrimidine nucleoside triphosphate catabolic process →	+0.145	+0.499	.006	.003	1	12
BREAST	Epinephrine metabolic process →	+0.872	+1.091	.002	<.001	3	9
BONE	tRNA threonylcarbamoyladenosine modification →	+0.164	+0.734	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,744 associations by consensus.

Exploration

BOLA2 survival (RNA) · tumor vs normal (RNA) · all BOLA2 data types