BOLA1

Across TCGA pan-cancer cohorts, BOLA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated BOLA1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BOLA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BOLA1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and HNSC are the cancer types where BOLA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.933	0.780	.018	8	view →
LSCC	DFS	Median	II,III,IV	0.999	0.844	.009	4	view →
HNSC	DFS	Median	All	0.978	0.909	.045	2	view →
PDAC	DFS	Quartile	II,III,IV	0.950	0.629	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

BOLA1–UCEC (DFS)

Open the UCEC breakdown →