BOLA1

Across TCGA patient cohorts, BOLA1 mutation is significantly associated with the RNA expression of many other genes, with 439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BOLA1-associated genes across cancer lineages are MIR7702, MTND3P1, and SNRPGP12. Each is linked with BOLA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BOLA1-to-partner and partner-to-BOLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by BOLA1-low versus BOLA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA1→partner) and Y-score (partner→BOLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.309	+4.738	<.001	.002	3	2
COAD	MTND3P1 →	+0.593	+5.602	<.001	.004	3	1
COAD	SNRPGP12 →	+0.608	+5.435	<.001	.005	3	1
COAD	AGGF1P9 →	+0.166	+6.251	<.001	.001	3	1
COAD	SOD1P2 →	+0.497	+5.145	<.001	.007	3	1
COAD	MTND3P13 →	+0.221	+5.893	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

MIR7702 by BOLA1 expression — UCEC

Explore this box plot interactively →