BOLA1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BOLA1 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BOLA1-associated genes across cancer lineages are p62 Lck ligand. Each is linked with BOLA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BOLA1-to-partner and partner-to-BOLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by BOLA1-low versus BOLA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA1→partner) and Y-score (partner→BOLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECp62 Lck ligand →+0.458+2.817.021.03621
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

p62 Lck ligand by BOLA1 expression — UCEC

Box plot of p62 Lck ligand in BOLA1-low vs BOLA1-high samples in UCEC.

Explore this box plot interactively →

Exploration