BOLA1

Across TCGA cell cohorts, BOLA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,899 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BOLA1-associated GO terms across cancer lineages are ATP synthesis coupled electron transport, Mitochondrial ATP synthesis coupled electron transport, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with BOLA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both BOLA1-to-partner and partner-to-BOLA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP synthesis coupled electron transport grouped by BOLA1-low versus BOLA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BOLA1→partner) and Y-score (partner→BOLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.102	+0.881	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial ATP synthesis coupled electron transport →	+0.102	+0.881	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven mitochondrial ATP synthesis →	+0.119	+1.126	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.121	+1.020	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Aerobic electron transport chain →	+0.099	+0.829	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Respiratory electron transport chain →	+0.100	+0.838	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,899 associations by consensus.

ATP synthesis coupled electron transport by BOLA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →