BOD1L2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BOD1L2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated BOD1L2 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher BOD1L2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated BOD1L2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SARC, SKCM, and UCEC are the cancer types where BOD1L2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCDFSMedianAll0.0950.632.0026view →
SKCMDFSMedianAll0.0610.208.0076view →
UCECDFSMedianAll1.0000.636.0424view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration