BOD1L1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BOD1L1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated BOD1L1 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BOD1L1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BOD1L1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where BOD1L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileAll0.6890.881.00436view →
CCRCCDFSTertileIII,IV0.8390.414.00717view →
PDACDFSTertileIV0.9340.231.02412view →
GBMOSTertileAll0.5110.239.00611view →
LUADOSTertileIII,IV0.7240.176.02010view →
COADDFSMedianII,III,IV1.0000.896.0476view →
LSCCDFSTertileIII,IV0.8381.000.0363view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

BOD1L1–HNSC (DFS)

Kaplan–Meier survival curve for BOD1L1 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration