BOD1L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BOD1L1 mutation is significantly associated with the RNA expression of many other genes, with 5,673 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BOD1L1-associated genes across cancer lineages are COX4I2, PSMC3IP, and NCAPG. Each is linked with BOD1L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BOD1L1-to-partner and partner-to-BOD1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX4I2 grouped by BOD1L1-low versus BOD1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOD1L1→partner) and Y-score (partner→BOD1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCOX4I2 →-0.459-1.653.008<.00136
UCECPSMC3IP →+0.545+1.368<.001<.00136
LUADNCAPG →+0.765+3.834<.001<.00135
SKCMRAMP2 →-0.683-2.209.003.00935
LUADKIF2C →+0.872+2.999<.001<.00135
LUADEME1 →+0.615+1.938<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,673 associations by consensus.

COX4I2 by BOD1L1 expression — UCEC

Box plot of COX4I2 in BOD1L1-low vs BOD1L1-high samples in UCEC.

Explore this box plot interactively →

Exploration