BOD1L1

Across TCGA patient cohorts, BOD1L1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BOD1L1-associated genes across cancer lineages are Caspase-7-cleavedD198, 4E-BP1, and ATM. Each is linked with BOD1L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BOD1L1-to-partner and partner-to-BOD1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by BOD1L1-low versus BOD1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOD1L1→partner) and Y-score (partner→BOD1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.589	+2.078	<.001	<.001	3	4
LUAD	4E-BP1 →	+0.252	+1.887	.036	.029	3	3
SKCM	ATM →	-0.410	-3.169	.013	.017	3	3
LUAD	14-3-3_beta →	-0.146	-2.205	.007	.010	3	2
LUAD	FoxM1 →	+0.417	+2.355	<.001	.017	3	2
LUAD	PCNA →	+0.257	+1.749	<.001	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Caspase-7-cleavedD198 by BOD1L1 expression — UCEC

Explore this box plot interactively →