BOD1L1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BOD1L1 mutation is significantly associated with the RNA expression of many other genes, with 1,150 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BOD1L1-associated genes across cancer lineages are FAM47A, PSMB6, and CCDC134. Each is linked with BOD1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BOD1L1-to-partner and partner-to-BOD1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by BOD1L1-low versus BOD1L1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BOD1L1→partner) and Y-score (partner→BOD1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSFAM47A →+0.009+3.392<.001.00732
SKINPSMB6 →+0.447+3.067.002.00932
LARGE_INTESTINECCDC134 →+0.670+2.716<.001<.00132
BLOOD_LeukemiaJOSD1 →+0.482+2.548.004.00632
LARGE_INTESTINEPPM1A →+0.483+2.043<.001.00132
LARGE_INTESTINEZC3H14 →+0.578+3.459<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,150 associations by consensus.

FAM47A by BOD1L1 expression — OESOPHAGUS

Box plot of FAM47A in BOD1L1-low vs BOD1L1-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration