Across TCGA patient cohorts, BNIP5 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BNIP5-associated genes across cancer lineages are mTOR_pS2448, Rad50, and PI3K-p85. Each is linked with BNIP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BNIP5-to-partner and partner-to-BNIP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIP5→partner) and Y-score (partner→BNIP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.135	-1.502	.013	.030	3	2
UCEC	Rad50 →	-0.281	-2.736	.001	<.001	3	2
SKCM	PI3K-p85 →	+0.173	+2.235	.017	.005	3	2
UCEC	eIF4G →	+0.311	+2.807	.006	.003	3	1
UCEC	Gab2 →	+0.302	+2.247	.021	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.133	-1.489	.032	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

BNIP5 survival (RNA) · tumor vs normal (RNA) · all BNIP5 data types