Across TCGA cell cohorts, BNIP5 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BNIP5-associated genes across cancer lineages are IFNA1, OR10AG1, and OR2W5. Each is linked with BNIP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BNIP5-to-partner and partner-to-BNIP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIP5→partner) and Y-score (partner→BNIP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	IFNA1 →	+0.030	+4.807	<.001	.006	3	2
LARGE_INTESTINE	OR10AG1 →	+0.005	+3.700	<.001	.009	3	2
BLOOD_Myeloma	OR2W5 →	+0.030	+4.807	<.001	.006	3	1
LIVER	OTOL1 →	+0.017	+3.977	<.001	.006	3	1
LIVER	TNMD →	+0.428	+3.977	<.001	.006	3	1
LARGE_INTESTINE	PLA2G5 →	+0.128	+2.994	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

BNIP5 survival (RNA) · tumor vs normal (RNA) · all BNIP5 data types