BNIP3P9

Across TCGA pan-cancer cohorts, BNIP3P9 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BNIP3P9 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher BNIP3P9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BNIP3P9 expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRC show a favorable association.

LUSC, CESC, and KIRC are the cancer types where BNIP3P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.150	0.779	.001	64	view →
CESC	OS	Tertile	All	0.903	0.741	<.001	36	view →
KIRC	DFS	Quartile	All	0.750	0.552	<.001	35	view →
LGG	DFS	Quartile	All	0.607	0.778	<.001	31	view →
SKCM	OS	Tertile	All	0.850	0.754	.002	28	view →
THCA	OS	Quartile	All	0.974	0.996	.001	25	view →
ACC	OS	Tertile	III,IV	0.713	0.314	.015	23	view →
READ	OS	Tertile	III,IV	0.345	0.718	.022	21	view →
SARC	OS	Median	All	0.884	0.797	.008	17	view →
GBM	DFS	Median	All	0.303	0.180	.022	12	view →
DLBC	DFS	Quartile	All	0.516	1.000	.010	10	view →
LAML	DFS	Quartile	All	0.616	0.268	.011	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BNIP3P9–LUSC (DFS)

Open the LUSC breakdown →