Across TCGA pan-cancer cohorts, BNIP3P7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BNIP3P7’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where BNIP3P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BNIP3P7 is over-expressed in tumor.
THCA and LUAD are the cancer types where BNIP3P7 tumor–normal differential expression is most reproducible.