Across TCGA pan-cancer cohorts, BNIP3P42 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BNIP3P42’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where BNIP3P42 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BNIP3P42 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
STAD, THCA, and LUSC are the cancer types where BNIP3P42 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P42 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.