BNIP3P39

Across TCGA pan-cancer cohorts, BNIP3P39 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated BNIP3P39 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher BNIP3P39 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BNIP3P39 expression acts as an unfavorable survival marker, although some lineages such as BRCA and STAD show a favorable association.

LIHC, DLBC, and CESC are the cancer types where BNIP3P39 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.438	0.590	<.001	74	view →
DLBC	DFS	Tertile	II,III,IV	0.124	0.884	<.001	72	view →
CESC	OS	Quartile	All	0.802	0.894	.006	42	view →
UCEC	OS	Median	All	0.909	0.942	.009	30	view →
MESO	OS	Tertile	II,III,IV	0.252	0.425	.034	18	view →
LGG	DFS	Tertile	All	0.183	0.418	<.001	18	view →
LUSC	DFS	Quartile	All	0.676	0.782	.010	10	view →
ACC	DFS	Tertile	III,IV	0.061	0.378	.024	9	view →
KIRP	OS	Quartile	II,III,IV	0.160	0.663	.016	6	view →
READ	DFS	Quartile	All	0.307	0.637	.010	6	view →
ESCA	DFS	Quartile	All	0.245	0.424	.014	6	view →
BRCA	OS	Median	IV	0.702	0.367	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

BNIP3P39–LIHC (DFS)

Open the LIHC breakdown →