BNIP3P38

Across TCGA pan-cancer cohorts, BNIP3P38 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated BNIP3P38 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher BNIP3P38 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P38 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

THCA, LIHC, and OV are the cancer types where BNIP3P38 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.240	0.931	.003	27	view →
LIHC	DFS	Tertile	All	0.269	0.550	.004	18	view →
OV	OS	Tertile	II,III,IV	0.372	0.304	.031	16	view →
THYM	DFS	Tertile	II,III,IV	0.304	0.818	.004	12	view →
KIRC	DFS	Tertile	III,IV	0.492	0.760	.018	12	view →
ESCA	DFS	Quartile	IV	0.826	0.322	.040	12	view →
KIRP	DFS	Tertile	All	0.717	0.878	.013	12	view →
HNSC	DFS	Tertile	All	0.753	0.607	.028	12	view →
LAML	DFS	Median	All	0.673	0.459	.025	12	view →
SKCM	DFS	Tertile	III,IV	0.202	0.607	.001	9	view →
PCPG	DFS	Tertile	All	0.086	0.845	.022	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

BNIP3P38–THCA (OS)

Open the THCA breakdown →