BNIP3P36

Across TCGA pan-cancer cohorts, BNIP3P36 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of BNIP3P36’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BNIP3P36 RNA is repressed in tumor relative to normal tissue. In most cancer types BNIP3P36 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where BNIP3P36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.043	<.001	9	view →
KICH	All	II,III,IV	−0.062	.012	3	view →
LIHC	All	All	+0.029	.024	2	view →
LUSC	All	All	−0.013	.031	2	view →
KIRP	Male	All	−0.063	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

BNIP3P36–KIRC

Open the KIRC breakdown →