BNIP3P35

Across TCGA pan-cancer cohorts, BNIP3P35 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated BNIP3P35 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher BNIP3P35 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BNIP3P35 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SARC show a favorable association.

PAAD, MESO, and COAD are the cancer types where BNIP3P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	All	0.068	0.468	<.001	63	view →
MESO	DFS	Tertile	II,III,IV	0.074	0.382	<.001	63	view →
COAD	OS	Tertile	All	0.163	0.870	<.001	54	view →
KIRC	OS	Tertile	All	0.441	0.642	.002	48	view →
UCEC	OS	Tertile	III,IV	0.690	0.839	.026	42	view →
LGG	OS	Tertile	All	0.412	0.817	<.001	33	view →
ESCA	DFS	Tertile	III,IV	0.607	0.363	.038	18	view →
LUSC	DFS	Tertile	All	0.499	0.753	.013	18	view →
LUAD	OS	Tertile	II,III,IV	0.150	0.677	.008	18	view →
STAD	DFS	Tertile	III,IV	0.221	0.490	.038	15	view →
SARC	DFS	Tertile	All	0.825	0.322	.016	15	view →
TGCT	DFS	Median	All	0.889	0.771	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

BNIP3P35–PAAD (DFS)

Open the PAAD breakdown →