BNIP3P30

Across TCGA pan-cancer cohorts, BNIP3P30 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BNIP3P30 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BNIP3P30 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BNIP3P30 expression acts as an unfavorable survival marker, although some lineages such as ACC and MESO show a favorable association.

ACC, MESO, and COAD are the cancer types where BNIP3P30 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.856	0.545	.002	71	view →
MESO	OS	Tertile	All	0.582	0.317	.002	69	view →
COAD	DFS	Tertile	All	0.511	0.703	.012	63	view →
OV	OS	Median	IV	0.750	0.496	.003	40	view →
UVM	OS	Quartile	II,III,IV	0.804	0.467	.001	38	view →
LGG	DFS	Tertile	All	0.809	0.683	.004	26	view →
READ	DFS	Tertile	IV	0.141	0.671	<.001	21	view →
UCS	OS	Median	IV	0.240	0.616	.019	18	view →
BRCA	OS	Median	III,IV	0.880	0.780	.012	13	view →
GBM	OS	Tertile	All	0.358	0.236	.026	11	view →
BLCA	DFS	Tertile	IV	0.194	0.451	.031	11	view →
CHOL	DFS	Tertile	III,IV	1.000	0.182	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BNIP3P30–ACC (DFS)

Open the ACC breakdown →