BNIP3P29

Across TCGA pan-cancer cohorts, BNIP3P29 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated BNIP3P29 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BNIP3P29 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P29 expression acts as an unfavorable survival marker, although some lineages such as KIRP and GBM show a favorable association.

KIRC, UCEC, and ACC are the cancer types where BNIP3P29 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.515	0.673	.002	38	view →
UCEC	DFS	Tertile	All	0.859	0.911	.004	36	view →
ACC	DFS	Tertile	All	0.166	0.598	.003	30	view →
KIRP	DFS	Quartile	II,III,IV	0.907	0.607	.010	29	view →
GBM	DFS	Tertile	All	0.521	0.226	.007	27	view →
STAD	OS	Tertile	All	0.612	0.721	.015	17	view →
OV	OS	Median	III,IV	0.872	0.801	.016	16	view →
SKCM	DFS	Quartile	All	0.871	0.733	.009	12	view →
MESO	OS	Quartile	II,III,IV	0.231	0.630	.025	9	view →
PAAD	DFS	Tertile	All	0.399	0.512	.039	8	view →
LGG	DFS	Quartile	All	0.635	0.805	.020	4	view →
THCA	DFS	Quartile	All	0.972	0.921	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

BNIP3P29–KIRC (OS)

Open the KIRC breakdown →