BNIP3P28

Across TCGA pan-cancer cohorts, BNIP3P28 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BNIP3P28 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher BNIP3P28 RNA is associated with better overall survival. In most high-consensus cancer types, elevated BNIP3P28 expression acts as an unfavorable survival marker, although some lineages such as MESO and BRCA show a favorable association.

MESO, BRCA, and UCEC are the cancer types where BNIP3P28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	II,III,IV	0.516	0.278	<.001	120	view →
BRCA	OS	Median	III,IV	0.903	0.769	.001	35	view →
UCEC	DFS	Median	IV	0.729	0.226	.001	32	view →
UCS	OS	Median	All	0.535	0.215	.006	28	view →
ESCA	DFS	Median	III,IV	0.475	0.225	.002	22	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	18	view →
KICH	DFS	Median	All	0.969	0.716	.005	16	view →
KIRP	OS	Quartile	All	0.976	0.916	.031	13	view →
THCA	OS	Median	II,III,IV	0.965	0.334	.025	12	view →
LUAD	DFS	Median	IV	0.327	0.761	.001	12	view →
ACC	OS	Tertile	III,IV	0.918	0.435	.032	5	view →
CHOL	DFS	Tertile	II,III,IV	0.700	0.159	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BNIP3P28–MESO (OS)

Open the MESO breakdown →