BNIP3P27

Across TCGA pan-cancer cohorts, BNIP3P27 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated BNIP3P27 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher BNIP3P27 RNA is associated with better overall survival. In most high-consensus cancer types, elevated BNIP3P27 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

BLCA, KIRC, and LIHC are the cancer types where BNIP3P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.541	0.340	<.001	106	view →
KIRC	DFS	Median	All	0.548	0.701	<.001	76	view →
LIHC	DFS	Quartile	All	0.411	0.606	<.001	51	view →
BRCA	OS	Tertile	IV	0.863	0.285	.002	49	view →
PAAD	OS	Quartile	All	0.806	0.286	.001	41	view →
PRAD	DFS	Median	All	0.832	0.934	<.001	32	view →
LGG	DFS	Median	All	0.785	0.873	.001	23	view →
UVM	DFS	Median	III,IV	0.253	0.807	.001	23	view →
MESO	OS	Tertile	III,IV	0.696	0.494	.014	21	view →
ACC	DFS	Median	II,III,IV	0.289	0.682	.004	20	view →
THCA	OS	Quartile	III,IV	0.911	0.986	.017	18	view →
LUSC	OS	Median	III,IV	0.650	0.387	.008	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

BNIP3P27–BLCA (OS)

Open the BLCA breakdown →