BNIP3P22

Across TCGA patient cohorts, BNIP3P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,963 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BNIP3P22-associated GO terms across cancer lineages are Regulation of DNA-templated transcription elongation, Regulation of RNA splicing, and Regulation of DNA-templated transcription initiation. Each is linked with BNIP3P22 in more than 24 cancer types. Because this analysis shows association rather than direction, both BNIP3P22-to-partner and partner-to-BNIP3P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription elongation grouped by BNIP3P22-low versus BNIP3P22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIP3P22→partner) and Y-score (partner→BNIP3P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA-templated transcription elongation →	+0.067	+0.316	<.001	<.001	3	24
STAD	Regulation of RNA splicing →	+0.060	+0.152	<.001	<.001	3	24
ESCA	Regulation of DNA-templated transcription initiation →	+0.066	+0.312	<.001	<.001	3	23
ESCA	Regulation of DNA repair →	+0.062	+0.307	<.001	<.001	3	23
DLBC	DNA-templated transcription initiation →	+0.057	+0.158	.006	.005	1	25
ESCA	Transcription initiation at RNA polymerase II promoter →	+0.060	+0.306	<.001	<.001	2	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,963 associations by consensus.

Regulation of DNA-templated transcription elongation by BNIP3P22 expression — ESCA

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