Across TCGA pan-cancer cohorts, BNIP3P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of BNIP3P2’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where BNIP3P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BNIP3P2 is over-expressed in tumor.
LUAD are the cancer types where BNIP3P2 tumor–normal differential expression is most reproducible.