BNIP3P18

Across TCGA pan-cancer cohorts, BNIP3P18 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of BNIP3P18’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where BNIP3P18 RNA is repressed in tumor relative to normal tissue. In most cancer types BNIP3P18 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and KIRC are the cancer types where BNIP3P18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.617	<.001	11	view →
LUSC	Male	All	−0.284	<.001	5	view →
KIRC	All	All	+0.070	.005	4	view →
LUAD	All	II,III,IV	−0.222	.011	3	view →
PRAD	All	All	+0.572	.022	2	view →
LIHC	All	All	+0.152	.002	2	view →
KICH	All	All	−0.072	.017	2	view →
ESCA	All	All	−0.213	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

BNIP3P18–THCA

Open the THCA breakdown →