BNIP3P16

Across TCGA pan-cancer cohorts, BNIP3P16 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of BNIP3P16’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BNIP3P16 RNA is repressed in tumor relative to normal tissue. In most cancer types BNIP3P16 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and BRCA are the cancer types where BNIP3P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.389	<.001	7	view →
THCA	All	All	−0.383	<.001	6	view →
BRCA	All	II,III,IV	+0.167	.031	4	view →
LIHC	All	All	+0.056	.011	4	view →
KIRP	All	IV	+0.515	.037	2	view →
CHOL	All	All	+0.172	.009	2	view →
LUAD	All	All	+0.205	.045	1	view →
STAD	Male	All	+0.179	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

BNIP3P16–KICH

Open the KICH breakdown →