BNIP3P13

Across TCGA pan-cancer cohorts, BNIP3P13 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated BNIP3P13 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BNIP3P13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BNIP3P13 expression acts as an unfavorable survival marker, although some lineages such as THCA show a favorable association.

KIRC, BRCA, and LUAD are the cancer types where BNIP3P13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.305	0.663	.001	90	view →
BRCA	OS	Tertile	III,IV	0.278	0.839	<.001	48	view →
LUAD	OS	Tertile	III,IV	0.183	0.679	<.001	36	view →
LGG	DFS	Tertile	All	0.677	0.864	<.001	18	view →
SKCM	OS	Tertile	III,IV	0.216	0.721	.001	15	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
THCA	DFS	Median	IV	0.867	0.682	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

BNIP3P13–KIRC (DFS)

Open the KIRC breakdown →