BNIP3

Across TCGA patient cohorts, BNIP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,654 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BNIP3-associated proteins across cancer lineages are KDM3A, P4HA1, and LDHA. Each is linked with BNIP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both BNIP3-to-partner and partner-to-BNIP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BNIP3 versus KDM3A in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BNIP3→partner) and Y-score (partner→BNIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KDM3A →	+0.584	+0.912	<.001	<.001	3	7
GBM	P4HA1 →	+0.697	+0.790	<.001	<.001	3	7
HNSC	LDHA →	+0.536	+0.830	<.001	<.001	3	6
HNSC	NDRG1 →	+0.975	+1.147	<.001	<.001	3	6
LSCC	BNIP3_S151 →	+1.007	+1.199	<.001	<.001	3	6
GBM	RTN1 →	-0.547	-0.547	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,654 associations by consensus.

BNIP3 vs KDM3A — LSCC

Explore this scatter interactively →