BMX

Across TCGA patient cohorts, BMX mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMX-associated genes across cancer lineages are eEF2, INPP4B, and ASNS. Each is linked with BMX in more than 1 cancer types. Because this analysis shows association rather than direction, both BMX-to-partner and partner-to-BMX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by BMX-low versus BMX-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMX→partner) and Y-score (partner→BMX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.238	+1.415	.030	.043	3	2
UCEC	INPP4B →	-0.285	-2.906	.003	.001	3	2
UCEC	ASNS →	+0.354	+2.321	.001	<.001	3	2
UCEC	ATM →	-0.536	-3.893	<.001	<.001	3	2
UCEC	Cyclin-B1 →	+0.682	+2.584	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.088	-1.673	.004	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

eEF2 by BMX expression — UCEC

Explore this box plot interactively →