BMT2

Across TCGA patient cohorts, BMT2 mutation is significantly associated with the RNA expression of many other genes, with 3,235 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMT2-associated genes across cancer lineages are AURKB, LONP1, and CFI. Each is linked with BMT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BMT2-to-partner and partner-to-BMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AURKB grouped by BMT2-low versus BMT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMT2→partner) and Y-score (partner→BMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AURKB →	+0.551	+2.917	.001	<.001	3	3
UCEC	LONP1 →	+0.659	+2.425	<.001	<.001	3	3
LUAD	CFI →	-1.270	-3.435	<.001	.005	3	3
LUAD	EME1 →	+0.969	+3.227	<.001	.009	3	3
UCEC	CHAF1B →	+0.636	+1.906	<.001	<.001	3	3
LUAD	CCNF →	+0.797	+3.459	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,235 associations by consensus.

AURKB by BMT2 expression — UCEC

Explore this box plot interactively →