BMT2

Across TCGA cell cohorts, BMT2 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMT2-associated genes across cancer lineages are SLC15A5, OR11H1, and OR10H2. Each is linked with BMT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMT2-to-partner and partner-to-BMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by BMT2-low versus BMT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMT2→partner) and Y-score (partner→BMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC15A5 →	+0.022	+4.643	<.001	.005	3	2
LUNG_NSCLC_LUAD	OR11H1 →	+0.041	+4.371	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR10H2 →	+0.030	+4.371	.002	.005	3	1
LUNG_NSCLC_LUAD	SPDYE4 →	+0.037	+4.544	.003	.003	3	1
LUNG_NSCLC_LUAD	C9orf92 →	+0.133	+4.212	.007	.007	3	1
LUNG_NSCLC_LUAD	OR52B4 →	+0.014	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

SLC15A5 by BMT2 expression — BLOOD_Lymphoma

Explore this box plot interactively →