BMS1P7

Across TCGA patient cohorts, BMS1P7 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMS1P7-associated genes across cancer lineages are mTOR, ATM, and Beclin. Each is linked with BMS1P7 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMS1P7-to-partner and partner-to-BMS1P7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR grouped by BMS1P7-low versus BMS1P7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMS1P7→partner) and Y-score (partner→BMS1P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR →	-0.294	-3.169	<.001	.020	3	1
UCEC	ATM →	-0.883	-2.986	<.001	.035	3	1
UCEC	Beclin →	+0.115	+3.169	.027	.020	3	1
UCEC	INPP4B →	-0.467	-3.000	.008	.036	2	1
UCEC	PCNA →	+0.270	+3.169	.022	.020	2	1
UCEC	Tuberin_pT1462 →	+0.312	+2.817	.013	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

mTOR by BMS1P7 expression — UCEC

Explore this box plot interactively →