BMS1P20

Across TCGA patient cohorts, BMS1P20 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMS1P20-associated genes across cancer lineages are JNK_pT183_Y185, MEK1, and MIG-6. Each is linked with BMS1P20 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMS1P20-to-partner and partner-to-BMS1P20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by BMS1P20-low versus BMS1P20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMS1P20→partner) and Y-score (partner→BMS1P20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.236	-3.000	.007	.036	3	1
UCEC	MEK1 →	+0.588	+3.321	.002	.010	3	1
UCEC	MIG-6 →	+0.139	+2.179	.007	.034	3	1
UCEC	p62 Lck ligand →	+0.630	+2.817	<.001	.036	3	1
UCEC	STAT3_pY705 →	-0.697	-3.321	<.001	.010	3	1
UCEC	CD20 →	+0.152	+3.321	.027	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

JNK_pT183_Y185 by BMS1P20 expression — UCEC

Explore this box plot interactively →