Across TCGA pan-cancer cohorts, BMS1P14 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of BMS1P14’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where BMS1P14 RNA is repressed in tumor relative to normal tissue. In most cancer types BMS1P14 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA are the cancer types where BMS1P14 tumor–normal differential expression is most reproducible.