Across TCGA pan-cancer cohorts, BMS1P11 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BMS1P11’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where BMS1P11 RNA is repressed in tumor relative to normal tissue. In most cancer types BMS1P11 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
COAD and STAD are the cancer types where BMS1P11 tumor–normal differential expression is most reproducible.