Across TCGA patient cohorts, BMS1P1 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMS1P1-associated genes across cancer lineages are MEK1, Notch1, and AMPK_pT172. Each is linked with BMS1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMS1P1-to-partner and partner-to-BMS1P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMS1P1→partner) and Y-score (partner→BMS1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.521	+3.459	.004	.005	3	1
UCEC	Notch1 →	+0.144	+2.817	.042	.036	3	1
UCEC	AMPK_pT172 →	+0.405	+2.335	.049	.020	3	1
UCEC	STAT3_pY705 →	-0.388	-2.321	.003	.035	3	1
UCEC	Tuberin_pT1462 →	+0.238	+2.321	.040	.035	3	1
UCEC	XBP1 →	-0.192	-3.000	.006	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

BMS1P1 survival (RNA) · tumor vs normal (RNA) · all BMS1P1 data types