BMS1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BMS1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BMS1 data layer compared with 22 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher BMS1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BMS1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where BMS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.7380.928<.00143view →
PDACOSQuartileII,III,IV0.6720.971.00214view →
LUADDFSMedianIII,IV0.4090.941.01011view →
GBMOSMedianAll0.4910.291.0107view →
HNSCDFSQuartileIV0.6350.914.0221view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BMS1–CCRCC (OS)

Kaplan–Meier survival curve for BMS1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration