BMS1

Across TCGA cell cohorts, BMS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,288 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BMS1-associated GO terms across cancer lineages are rRNA 5'-end processing, Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and DNA-templated DNA replication. Each is linked with BMS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both BMS1-to-partner and partner-to-BMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA 5'-end processing grouped by BMS1-low versus BMS1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMS1→partner) and Y-score (partner→BMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	rRNA 5'-end processing →	+0.162	+0.809	<.001	<.001	3	18
PANCREAS	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.162	+0.809	<.001	<.001	3	18
SOFT_TISSUE	DNA-templated DNA replication →	+0.110	+0.867	<.001	<.001	3	18
BLOOD_Myeloma	Maturation of SSU-rRNA →	+0.125	+0.955	<.001	.001	3	18
PANCREAS	DNA replication initiation →	+0.185	+0.810	<.001	<.001	3	18
SOFT_TISSUE	DNA replication →	+0.098	+0.851	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,288 associations by consensus.

rRNA 5'-end processing by BMS1 expression — PANCREAS

Explore this box plot interactively →