BMS1

Across TCGA cell cohorts, BMS1 mutation is significantly associated with the RNA expression of many other genes, with 928 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMS1-associated genes across cancer lineages are CCL16, VAX1, and DUXA. Each is linked with BMS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMS1-to-partner and partner-to-BMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL16 grouped by BMS1-low versus BMS1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMS1→partner) and Y-score (partner→BMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CCL16 →	+0.081	+4.432	.002	.003	3	2
CNS	VAX1 →	+0.637	+3.882	<.001	.006	3	2
CNS	DUXA →	+0.046	+3.874	.001	.006	3	2
LUNG_NSCLC_LUAD	UPF2 →	+0.543	+3.358	.002	.003	3	2
LUNG_NSCLC_LUAD	KIF5B →	+0.516	+3.358	.008	.003	3	2
BLOOD_Leukemia	AQP12A →	+0.045	+3.099	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 928 associations by consensus.

CCL16 by BMS1 expression — STOMACH

Explore this box plot interactively →