Across TCGA patient cohorts, BMPR2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,505 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BMPR2-associated genes across cancer lineages are RPL23AP18, SEMA3G, and PTPRB. Each is linked with BMPR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BMPR2-to-partner and partner-to-BMPR2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR2→partner) and Y-score (partner→BMPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL23AP18 →	+1.263	+0.312	.006	.009	3	3
CCRCC	SEMA3G →	+1.358	+0.183	<.001	.009	3	3
CCRCC	PTPRB →	+1.099	+0.219	<.001	<.001	3	3
CCRCC	RAMP2 →	+0.742	+0.146	<.001	.005	3	3
GBM	FAM13C →	+0.538	+0.259	<.001	<.001	3	3
CCRCC	CLEC3B →	+1.392	+0.228	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,505 associations by consensus.

Exploration

BMPR2 survival (RNA) · tumor vs normal (RNA) · all BMPR2 data types