Across TCGA cell cohorts, BMPR2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,231 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BMPR2-associated genes across cancer lineages are PIKFYVE, TRAK2, and ALS2. Each is linked with BMPR2 in more than 16 cancer types. Because this analysis shows association rather than direction, both BMPR2-to-partner and partner-to-BMPR2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR2→partner) and Y-score (partner→BMPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PIKFYVE →	+1.087	+1.131	<.001	<.001	3	17
LUNG_NSCLC_LUSC	TRAK2 →	+1.518	+1.655	<.001	<.001	3	17
LUNG_NSCLC_LUSC	ALS2 →	+1.215	+1.095	<.001	<.001	3	16
STOMACH	SECISBP2L →	+1.104	+1.280	<.001	.003	3	16
STOMACH	MAP3K2 →	+1.139	+0.920	<.001	.009	2	16
STOMACH	EXOC5 →	+1.087	+1.521	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,231 associations by consensus.

Exploration

BMPR2 survival (RNA) · tumor vs normal (RNA) · all BMPR2 data types