BMP8B

Across TCGA patient cohorts, BMP8B protein abundance is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BMP8B-associated genes across cancer lineages are SSTR5, TIMP3, and PLTP. Each is linked with BMP8B in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP8B-to-partner and partner-to-BMP8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMP8B versus SSTR5 in LSCC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP8B→partner) and Y-score (partner→BMP8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SSTR5 →	+2.672	+1.492	<.001	.003	3	2
COAD	TIMP3 →	-1.257	-0.985	.003	<.001	3	1
COAD	PLTP →	-1.324	-0.881	<.001	.001	3	1
COAD	CCL22 →	-1.005	-1.033	.001	.007	3	1
COAD	NECAB2 →	-0.160	-0.677	.005	.003	3	1
COAD	PRPH2 →	-0.575	-1.315	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

BMP8B vs SSTR5 — LSCC

Explore this scatter interactively →