BMP8B

Across TCGA cell cohorts, BMP8B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,681 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BMP8B-associated GO terms across cancer lineages are Regulation of myoblast fusion, Aerobic respiration, and Negative regulation of myoblast fusion. Each is linked with BMP8B in more than 11 cancer types. Because this analysis shows association rather than direction, both BMP8B-to-partner and partner-to-BMP8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by BMP8B-low versus BMP8B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP8B→partner) and Y-score (partner→BMP8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of myoblast fusion →	+0.129	+1.159	<.001	<.001	3	12
OESOPHAGUS	Aerobic respiration →	+0.121	+1.557	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.135	+1.328	.002	.001	2	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.141	+1.127	.001	<.001	2	12
STOMACH	ATP synthesis coupled electron transport →	+0.125	+1.239	<.001	<.001	3	11
STOMACH	Mitochondrial ATP synthesis coupled electron transport →	+0.125	+1.239	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,681 associations by consensus.

Regulation of myoblast fusion by BMP8B expression — STOMACH

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