BMP7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BMP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,833 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BMP7-associated GO terms across cancer lineages are Morphogenesis of an epithelial fold, Pericardium morphogenesis, and Regulation of hyaluranon cable assembly. Each is linked with BMP7 in more than 16 cancer types. Because this analysis shows association rather than direction, both BMP7-to-partner and partner-to-BMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Morphogenesis of an epithelial fold grouped by BMP7-low versus BMP7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP7→partner) and Y-score (partner→BMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCMorphogenesis of an epithelial fold →+1.998+3.610<.001<.001317
SOFT_TISSUEPericardium morphogenesis →+1.717+2.462<.001<.001315
BLOOD_MyelomaRegulation of hyaluranon cable assembly →+1.506+4.010<.001<.001314
BLOOD_MyelomaPositive regulation of hyaluranon cable assembly →+1.506+4.010<.001<.001314
SOFT_TISSUEPericardium development →+1.722+2.694<.001<.001313
BLOOD_MyelomaEmbryonic placenta morphogenesis →+1.726+3.268<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,833 associations by consensus.

Morphogenesis of an epithelial fold by BMP7 expression — LUNG_NSCLC_LUSC

Box plot of Morphogenesis of an epithelial fold in BMP7-low vs BMP7-high samples in LUNG_NSCLC_LUSC.

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Exploration